Dr Trang Nguyen
University Technology Sydney

Dr Nguyen is a research fellow and lecturer in Biomedical Engineering at University Technology Sydney (UTS) and the ACRF Image-X Institute. She was awarded First Class Honour in Bachelor of Engineering at The University of Queensland in 2010, followed by a Doctor of Philosophy conferred by The University of Sydney in 2015. She currently holds an Australian National Health and Medical Research Council (NHMRC) fellowship, a Cancer Institute New South Wales Fellowship and a Cancer Australia grant, totalling $1.2M in funding. Dr Nguyen is the lead physicist in two multi-institutional radiotherapy clinical trials: TROG 15.01 SPARK trial and TROG 17.03 LARK trial.
Dr Nguyen has authored and co-authored 25 high impact research papers in the field of medical physics. Her scientific career to date produced more than 40 journals in total. Two articles were mentioned in the editorials of Radiotherapy and Oncology and became the featured articles of their issues.

Abstract

Radiation therapy is the recommended treatment for 48% of all cancer patients world-wide.7 Despite this central role in cancer treatment, the radiation therapy treatments of today suffer from a major problem: whilst they routinely image patients prior to treatment, no anatomical information is typically available during treatment. Tumours are not static during treatment, so methods to monitor tumour motion during radiation targeting, are essential to ensure proper dose coverage. Our team have pioneered the development and clinical testing of a real-time radiotherapy method that can be used with standard cancer radiotherapy systems. This method, Kilovoltage Intrafraction Monitoring (KIM) improves accurate tumour tissue dose distributions and offers shorter treatment schedules. KIM is already the basis of two multicentre Trans-Tasman Radiation Oncology Group (TROG) clinical trials – the completed SPARK prostate cancer trial, and the current LARK liver cancer trial, open for accrual. KIM is the world first and only dynamic radiotherapy system capable of monitoring both the tumour translational and rotational motion.

In this presentation, I will introduce the concept of the KIM technology and stepping through the journey of this technology from conception to clinical translation.

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